Publications

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2025

Syed R, Rengasamy P, Rajagopalan S, Deiuliis JA, Maiseyeu A. MicroRNA 223 Enhances ABCA1 Protein Stability and Supports Efflux in Cholesterol-Burdened Macrophages. Cell Biochem Biophys. 2025 Jun;83(2):1943-1954.

2024

Hong NE, Chaplin A, Di L, Ravodina A, Bevan GH, Gao H, Asase C, Gangwar RS, Cameron MJ, Mignery M, Cherepanova O, Finn AV, Nayak L, Pieper AA, Maiseyeu A. Nanoparticle-based itaconate treatment recapitulates low-cholesterol/low-fat diet-induced atherosclerotic plaque resolution. Cell Rep. 2024 Nov 26;43(11):114911.

Switala L, Di L, Gao H, Asase C, Klos M, Rengasamy P, Fedyukina D, Maiseyeu A. Engineered nanoparticles promote cardiac tropism of AAV vectors. J Nanobiotechnology. 2024 May 3;22(1):223.

Switala L, Di L, Colantonio S, Lakshman B, Caceres TW, Reading JJ, Garcia-Buntley SS, Maiseyeu A. The Development and Characterization of Two Monoclonal Antibodies Against the Conjugates and Derivatives of the Immunometabolite Itaconate. ACS Omega. 2024 Dec 20;10(1):1110-1121.

2023

Edwards-Glenn JM, Fontes MT, Waigi EW, Costa TJ, Maiseyeu A, Webb RC, McCarthy CG, Wenceslau CF. Specialized Pro-resolving Mediator Improves Vascular Relaxation via Formyl Peptide Receptor-2. Am J Hypertens. 2023 Sep 15;36(10):542-550.

Di L, Thomas A, Switala L, Kalikasingh K, Lapping S, Nayak L, Maiseyeu A. Surface Geometry of Cargo-less Gold Nanoparticles Is a Driving Force for Selective Targeting of Activated Neutrophils to Reduce Thrombosis in Antiphospholipid Syndrome. Nano Lett. 2023 Nov 8;23(21):9690-9696.

2022

Nayak L, Sweet DR, Thomas A, Lapping SD, Kalikasingh K, Madera A, Vinayachandran V, Padmanabhan R, Vasudevan NT, Myers JT, Huang AY, Schmaier A, Mackman N, Liao X, Maiseyeu A, Jain MK. A targetable pathway in neutrophils mitigates both arterial and venous thrombosis. Sci Transl Med. 2022 Aug 31;14(660):eabj7465. 

Maiseyeu A, Di L, Ravodina A, Barajas-Espinosa A, Sakamoto A, Chaplin A, Zhong J, Gao H, Mignery M, Narula N, Finn AV, Rajagopalan S. Plaque-targeted, proteolysis-resistant, activatable and MRI-visible nano-GLP-1 receptor agonist targets smooth muscle cell differentiation in atherosclerosis. Theranostics. 2022 Mar 6;12(6):2741-2757.

2021

Di L, Maiseyeu A. Low-density lipoprotein nanomedicines: mechanisms of targeting, biology, and theranostic potential. Drug Deliv. 2021 Dec;28(1):408-421. 

2020

Jayaraj P, Narasimhulu CA, Maiseyeu A, Durairaj R, Rao S, Rajagopalan S, Parthasarathy S, Desikan R. Methoxyphenol derivatives as reversible inhibitors of myeloperoxidase as potential antiatherosclerotic agents. Future Med Chem. 2020 Jan;12(2):95-110. doi: 10.4155/fmc-2019-0080. Epub 2019 Nov 26. 

Ravodina AM, Badgeley MA, Rajagopalan S, Fedyukina DV, Maiseyeu A. Facile Cholesterol Loading with a New Probe ezFlux Allows for Streamlined Cholesterol Efflux Assays. ACS Omega. 2020 Sep 3;5(36):23289-23298.

Chaplin A, Gao H, Asase C, Rengasamy P, Park B, Skander D, Bebek G, Rajagopalan S, Maiseyeu A. Systemically-delivered biodegradable PLGA alters gut microbiota and induces transcriptomic reprogramming in the liver in an obesity mouse model. Sci Rep. 2020 Aug 14;10(1):13786.

Gangwar RS, Vinayachandran V, Rengasamy P, Chan R, Park B, Diamond-Zaluski R, Cara EA, Cha A, Das L, Asase C, Maiseyeu A, Deiuliis J, Zhong J, Mitzner W, Biswal S, Rajagopalan S. Differential contribution of bone marrow-derived infiltrating monocytes and resident macrophages to persistent lung inflammation in chronic air pollution exposure. Sci Rep. 2020 Sep 1;10(1):14348.

Reyes-Caballero H, Rao X, Sun Q, Warmoes MO, Lin P, Sussan TE, Park B, Fan TW, Maiseyeu A, Rajagopalan S, Girnun GD, Biswal S. Author Correction: Air pollution-derived particulate matter dysregulates hepatic Krebs cycle, glucose and lipid metabolism in mice. Sci Rep. 2020 Mar 16;10(1):5082. doi: 10.1038/s41598-020-60083-6. Erratum for: Sci Rep. 2019 Nov 22;9(1):17423. 

Chaplin A, Gao H, Asase C, Rengasamy P, Park B, Skander D, Bebek G, Rajagopalan S, Maiseyeu A. Publisher Correction: Systemically-delivered biodegradable PLGA alters gut microbiota and induces transcriptomic reprogramming in the liver in an obesity mouse model. Sci Rep. 2020 Sep 24;10(1):16010. doi: 10.1038/s41598-020-72446-0. Erratum for: Sci Rep. 2020 Aug 14;10(1):13786.

Before 2020

2019

Mog B, Asase C, Chaplin A, Gao H, Rajagopalan S, Maiseyeu A. Nano-Antagonist Alleviates Inflammation and Allows for MRI of Atherosclerosis. Nanotheranostics. 2019 Nov 1;3(4):342-355. doi: 10.7150/ntno.37391.

Reyes-Caballero H, Rao X, Sun Q, Warmoes MO, Lin P, Sussan TE, Park B, Fan TW, Maiseyeu A, Rajagopalan S, Girnun GD, Biswal S. Air pollution-derived particulate matter dysregulates hepatic Krebs cycle, glucose and lipid metabolism in mice. Sci Rep. 2019 Nov 22;9(1):17423.

2018

Yasmeen R, Shen Q, Lee A, Leung JH, Kowdley D, DiSilvestro DJ, Xu L, Yang K, Maiseyeu A, Bal NC, Periasamy M, Fadda P, Ziouzenkova O. Epiregulin induces leptin secretion and energy expenditure in high-fat diet-fed mice. J Endocrinol. 2018 Dec 1;239(3):377-388.

2017

Zhong J, Maiseyeu A, Rajagopalan S. Lipoprotein effects of incretin analogs and dipeptidyl peptidase 4 inhibitors. Clin Lipidol. 2015;10:103–112. 

2016

Yao Z, Mates JM, Cheplowitz AM, Hammer LP, Maiseyeu A, Phillips GS, Wewers MD, Rajaram MVS, Robinson JM, Anderson CL, Ganesan LP. Blood-Borne Lipopolysaccharide Is Rapidly Eliminated by Liver Sinusoidal Endothelial Cells via High-Density Lipoprotein. J Immunol 2016 

Maiseyeu A. Non-antigenic regulators of targeting for imaging and therapy. Adv Drug Deliv Rev. 2016;99:1. 

Bagalkot V, Deiuliis JA, Rajagopalan S, Maiseyeu A. “Eat me” imaging and therapy. Adv Drug Deliv Rev. 2016;99:2–11. 

Ganesan LP, Mates JM, Cheplowitz AM, Avila CL, Zimmerer JM, Yao Z, Maiseyeu A, Rajaram MVS, Robinson JM, Anderson CL. Scavenger receptor B1, the HDL receptor, is expressed abundantly in liver sinusoidal endothelial cells. Sci Rep. 2016;6:20646. 

2015

Bagalkot V, Badgeley MA, Kampfrath T, Deiuliis JA, Rajagopalan S, Maiseyeu A. Hybrid nanoparticles improve targeting to inflammatory macrophages through phagocytic signals. J Control Release. 2015;217:243–255. 

Zhong J, Maiseyeu A, Davis SN, Rajagopalan S. DPP4 in cardiometabolic disease: recent insights from the laboratory and clinical trials of DPP4 inhibition. Circ Res. 2015;116:1491–1504. 

2014

Liu C, Fonken LK, Wang A, Maiseyeu A, Bai Y, Wang T-Y, Maurya S, Ko Y-A, Periasamy M, Dvonch T, Morishita M, Brook RD, Harkema J, Ying Z, Mukherjee B, Sun Q, Nelson RJ, Rajagopalan S. Central IKKβ inhibition prevents air pollution mediated peripheral inflammation and exaggeration of type II diabetes. Part Fibre Toxicol. 2014;11:53. 

Rao X, Zhong J, Maiseyeu A, Gopalakrishnan B, Villamena FA, Chen L-C, Harkema JR, Sun Q, Rajagopalan S. CD36-dependent 7-ketocholesterol accumulation in macrophages mediates progression of atherosclerosis in response to chronic air pollution exposure. Circ Res. 2014;115:770–780. 

Maiseyeu A, Bagalkot V. In vitro uptake of apoptotic body mimicking phosphatidylserine-quantum dot micelles by monocytic cell line. Nanoscale Res Lett. 2014;9:176. 

Maiseyeu A, Yang H-Y, Ramanathan G, Yin F, Bard RL, Morishita M, Dvonch JT, Wang L, Spino C, Mukherjee B, Badgeley MA, Barajas-Espinosa A, Sun Q, Harkema J, Rajagopalan S, Araujo JA, Brook RD. No effect of acute exposure to coarse particulate matter air pollution in a rural location on high-density lipoprotein function. Inhal Toxicol. 2014;26:23–29. 

2013

Rajagopalan S, Badgeley MA, Maiseyeu A. Cholesterol Efflux Assay Probe Formulations, Methods of Making and Using. US Patent. 2013

Giri S, Xue H, Maiseyeu A, Kroeker R, Rajagopalan S, White RD, Zuehlsdorff S, Raman SV, Simonetti OP. Steady-state first-pass perfusion (SSFPP): a new approach to 3D first-pass myocardial perfusion imaging. Magn Reson Med. 2014;71:133–144. 

Liu C, Xu X, Bai Y, Wang T-Y, Rao X, Wang A, Sun L, Ying Z, Gushchina L, Maiseyeu A, Morishita M, Sun Q, Harkema JR, Rajagopalan S. Air pollution-mediated susceptibility to inflammation and insulin resistance: influence of CCR2 pathways in mice. Environ Health Perspect. 2014;122:17–26. 

Deiuliis J, Mihai G, Zhang J, Taslim C, Varghese JJ, Maiseyeu A, Huang K, Rajagopalan S. Renin-sensitive microRNAs correlate with atherosclerosis plaque progression. J Hum Hypertens. 2014;28:251–258.

Blazek A, Rutsky J, Osei K, Maiseyeu A, Rajagopalan S. Exercise-mediated changes in high-density lipoprotein: impact on form and function. Am Heart J. 2013;166:392–400. 

Sun L, Liu C, Xu X, Ying Z, Maiseyeu A, Wang A, Allen K, Lewandowski RP, Bramble LA, Morishita M, Wagner JG, Dvonch J, Sun Z, Yan X, Brook RD, Rajagopalan S, Harkema JR, Sun Q, Fan Z. Ambient fine particulate matter and ozone exposures induce inflammation in epicardial and perirenal adipose tissues in rats fed a high fructose diet. Part Fibre Toxicol. 2013;10:43. 

Mihai G, Varghese J, Kampfrath T, Gushchina L, Hafer L, Deiuliis J, Maiseyeu A, Simonetti OP, Lu B, Rajagopalan S. Aliskiren Effect on Plaque Progression in Established Atherosclerosis Using High Resolution 3D MRI (ALPINE): A Double-Blind Placebo-Controlled Trial. J Am Heart Assoc. 2013;2.

Sharkey-Toppen TP, Mihai G, Maiseyeu A, Tran T, Clymer BD, Simonetti OP, Raman SV. Improved in vivo human carotid artery wall T₂ estimation. Magn Reson Imaging. 2013;31:44–52. 

2012

Liu C, Desikan R, Ying Z, Gushchina L, Kampfrath T, Deiuliis J, Wang A, Xu X, Zhong J, Rao X, Sun Q, Maiseyeu A, Parthasarathy S, Rajagopalan S. Effects of a novel pharmacologic inhibitor of myeloperoxidase in a mouse atherosclerosis model. PLoS One. 2012;7:e50767. 

Xu X, Rao X, Wang T-Y, Jiang SY, Ying Z, Liu C, Wang A, Zhong M, Deiuliis JA, Maiseyeu A, Rajagopalan S, Lippmann M, Chen L-C, Sun Q. Effect of co-exposure to nickel and particulate matter on insulin resistance and mitochondrial dysfunction in a mouse model. Part Fibre Toxicol. 2012;9:40. 

Yang F, Zhang X, Maiseyeu A, Mihai G, Yasmeen R, DiSilvestro D, Maurya SK, Periasamy M, Bergdall KV, Duester G, Sen CK, Roy S, Lee LJ, Rajagopalan S, Ziouzenkova O. The prolonged survival of fibroblasts with forced lipid catabolism in visceral fat following encapsulation in alginate-poly-L-lysine. Biomaterials. 2012;33:5638–5649. 

Ying Z, Desikan R, Xu X, Maiseyeu A, Liu C, Sun Q, Ziouzenkova O, Parthasarathy S, Rajagopalan S. Modified methylenedioxyphenol analogs lower LDL cholesterol through induction of LDL receptor expression. J Lipid Res. 2012;53:879–887. 

Maiseyeu A, Badgeley MA, Kampfrath T, Mihai G, Deiuliis JA, Liu C, Sun Q, Parthasarathy S, Simon DI, Croce K, Rajagopalan S. In vivo targeting of inflammation-associated myeloid-related protein 8/14 via gadolinium immunonanoparticles. Arterioscler Thromb Vasc Biol. 2012;32:962–970. 

Deiuliis JA, Kampfrath T, Zhong J, Oghumu S, Maiseyeu A, Chen LC, Sun Q, Satoskar AR, Rajagopalan S. Pulmonary T cell activation in response to chronic particulate air pollution. Am J Physiol Lung Cell Mol Physiol. 2012;302:L399–409. 

Xu X, Rao X, Wang T-Y, Jiang SY, Ying Z, Liu C, Wang A, Zhong M, Deiuliis JA, Maiseyeu A. Effect of co-exposure to nickel and particulate matter on insulin resistance and mitochondrial dysfunction in a mouse model. Part Fibre Toxicol. 2012;9:40.

Bandyopadhyay S, Xia X, Maiseiyeu A, Mihai G, Rajagopalan S, Bong D. Z-Group Ketone Chain Transfer Agents for RAFT Polymer Nanoparticle Modification via Hydrazone Conjugation. Macromolecules. 2012; 11;45(17):6766-6773.

2011

Nenajdenko VG, Moiseev AM, Balenkova ES. A novel method for the oxidation of thiophenes. Synthesis of thiophene 1, 1-dioxides containing electron-withdrawing substituents. Russ Chem Bull. 2004;53:2241–2247.

Maiseyeu A, Mihai G, Roy S, Kherada N, Simonetti OP, Sen CK, Sun Q, Parthasarathy S, Rajagopalan S. Detection of macrophages via paramagnetic vesicles incorporating oxidatively tailored cholesterol ester: an approach for atherosclerosis imaging. Nanomedicine. 2010;5:1341–1356. 

Deiuliis JA, Kampfrath T, Ying Z, Maiseyeu A, Rajagopalan S. Lipoic acid attenuates innate immune infiltration and activation in the visceral adipose tissue of obese insulin resistant mice. Lipids. 2011;46:1021–1032.

Kampfrath T, Maiseyeu A, Ying Z, Shah Z, Deiuliis JA, Xu X, Kherada N, Brook RD, Reddy KM, Padture NP, Parthasarathy S, Chen LC, Moffatt-Bruce S, Sun Q, Morawietz H, Rajagopalan S. Chronic fine particulate matter exposure induces systemic vascular dysfunction via NADPH oxidase and TLR4 pathways. Circ Res. 2011;108:716–726. 

Reichert B, Yasmeen R, Jeyakumar SM, Yang F, Thomou T, Alder H, Duester G, Maiseyeu A, Mihai G, Harrison EH, Rajagopalan S, Kirkland JL, Ziouzenkova O. Concerted action of aldehyde dehydrogenases influences depot-specific fat formation. Mol Endocrinol. 2011;25:799–809. 

Shah Z, Pineda C, Kampfrath T, Maiseyeu A, Ying Z, Racoma I, Deiuliis J, Xu X, Sun Q, Moffatt-Bruce S, Villamena F, Rajagopalan S. Acute DPP-4 inhibition modulates vascular tone through GLP-1 independent pathways. Vascul Pharmacol. 2011;55:2–9. 

Shah Z, Kampfrath T, Deiuliis JA, Zhong J, Pineda C, Ying Z, Xu X, Lu B, Moffatt-Bruce S, Durairaj R, Sun Q, Mihai G, Maiseyeu A, Rajagopalan S. Long-term dipeptidyl-peptidase 4 inhibition reduces atherosclerosis and inflammation via effects on monocyte recruitment and chemotaxis. Circulation. 2011;124:2338–2349. 

2009

Maiseyeu A, Mihai G, Kampfrath T, Simonetti OP, Sen CK, Roy S, Rajagopalan S, Parthasarathy S. Gadolinium-containing phosphatidylserine liposomes for molecular imaging of atherosclerosis. J Lipid Res. 2009;50:2157–2163. 

2006

Moiseev AM, Balenkova ES, Nenajdenko VG. Thiophene 1, 1-dioxides as unique building blocks in modern organic synthesis and materials chemistry. Russ Chem Rev. 2006;75:1015.

Moiseev AM, Balenkova ES, Nenajdenko VG. [6+ 4] Cycloaddition reactions of acceptor thiophene dioxides: The synthesis of substituted azulenes. Russ Chem Bull. 2006;55:141–146.

Moiseev AM, Tyurin DD, Balenkova ES, Nenajdenko VG. Reactions of acceptor substituted thiophene-1, 1-dioxides with cyclopentadiene: control of selectivity by substitution. Tetrahedron. 2006;62:4139–4145.

Moiseev AM, Balenkova ES, Nenajdenko VG. Reactions of electron-withdrawing thiophene 1, 1-dioxides with furans. A novel reaction pathway. Russ Chem Bull. 2006;55:712–717.

2005

Nenajdenko VG, Moiseev AM, Balenkova ES. Reactions of acceptor thiophene 1, 1-dioxides with dienes. Synthesis of bisadducts. Russ Chem Bull. 2005;54:2182–2186.

Nenajdenko VG, Moiseev AM, Balenkova ES. Chemo-, regio-and stereoselective Diels-Alder reactions of EWG bearing thiophene-1, 1-dioxides. Tetrahedron. 2005;61:10880–10885.

2004

Krasovsky AL, Moiseev AM, Nenajdenko VG, Balenkova ES. Reaction of 2-Aminothiazoles and Their Benzo-and Naphtho Derivatives with β-Sulfonyltrifluoromethylvinyldiols. Chem Heterocycl Compd . 2004;40:667–675.

2002

Krasovsky AL, Moiseev AM, Nenajdenko VG, Balenkova ES. Synthesis of New Fluorine Containing Triazolo-and Tetrazolopyrimidines. Synthesis . 2002;2002:901–905.

Krasovsky AL, Moiseev AM, Nenajdenko VG, Balenkova ES. Cyclocondensation of 2-Amino-1, 3, 4-thiadiazoles with β-Sulfonylvinyltrifluoromethyldiols. Chem Heterocycl Compd . 2002;38:231–237.