Employs Nanotechnology to Probe Cardiometabolic Disease
Principal Investigator: Andrei Maiseyeu, PhD
After receiving Ph.D. in Organic Chemistry from M.V. Lomonosov Moscow State University, I joined an imaging and cardiovascular biology lab at the Ohio State University, Heart and Lung Research Institute (DHLRI) as a post-doctoral fellow. At first, I was puzzled by single-use labware: during my PhD work, thorough hand-washing of used labware was a grueling ritual and, occasionally, a ‘reward’ for successful synthesis. Starting with discovery of disposable plastic flasks that biologists routinely used, I learned many intricacies of medical research. Fast forward 10 years, in November 2016, I joined the faculty at Case Western Reserve University with the goal to elucidate mechanisms of cardiovascular disease through nanotechnology and chemistry. See my biosketch here.
Medical Student: Matt Mignery
My name is Matt Mignery, and I am currently a first-year medical student at Case Western. I was born and raised in Columbus, OH, but grew up a Michigan football fan. I majored in biochemistry at Miami University in Oxford, OH, where I worked in Dr. Rick Page’s Structural Biology and Biophysics lab. We investigated the crystal structure of the mitochondrial protein Mortalin (its nucleotide-binding domain) in various states using x-ray crystallography. Currently, I work in Dr. Maiseyeu’s lab where we are further elucidating atherosclerotic macrophage metabolism along its M1/M2 polarization spectrum. I enjoy hiking, reading for leisure, and playing chess.
This could be you!Contact us if you are interested in joining our team!